| Middle Island to Sacile | 4,089.09 mi (6,580.76 km) |
| Middle Island to Sala Consilina | 4,419.89 mi (7,113.13 km) |
| Middle Island to Salemi | 4,389.90 mi (7,064.86 km) |
| Middle Island to Salerno | 4,372.26 mi (7,036.48 km) |
| Middle Island to Salo | 4,017.60 mi (6,465.70 km) |
| Middle Island to Salsomaggiore Terme | 4,019.18 mi (6,468.24 km) |
| Middle Island to Saluzzo | 3,916.12 mi (6,302.39 km) |
| Middle Island to Salzano | 4,087.24 mi (6,577.78 km) |
| Middle Island to Samarate | 3,941.96 mi (6,343.98 km) |
| Middle Island to San Benedetto del Tronto | 4,251.76 mi (6,842.55 km) |
| Middle Island to San Biagio di Callalta | 4,093.38 mi (6,587.66 km) |
| Middle Island to San Bonifacio | 4,056.15 mi (6,527.74 km) |
| Middle Island to San Casciano in Val di Pesa | 4,109.89 mi (6,614.23 km) |
| Middle Island to San Cataldo | 4,456.75 mi (7,172.45 km) |
| Middle Island to San Cesareo | 4,244.44 mi (6,830.77 km) |
