| Middle Island to Orbetello | 4,152.50 mi (6,682.81 km) |
| Middle Island to Oria | 4,505.58 mi (7,251.04 km) |
| Middle Island to Oristano | 4,121.50 mi (6,632.91 km) |
| Middle Island to Orta Nova | 4,390.17 mi (7,065.29 km) |
| Middle Island to Orte | 4,203.55 mi (6,764.95 km) |
| Middle Island to Ortona | 4,295.66 mi (6,913.19 km) |
| Middle Island to Orvieto | 4,182.45 mi (6,731.00 km) |
| Middle Island to Orzinuovi | 3,998.31 mi (6,434.67 km) |
| Middle Island to Osimo | 4,215.66 mi (6,784.45 km) |
| Middle Island to Ospitaletto | 3,999.35 mi (6,436.33 km) |
| Middle Island to Ostuni | 4,494.49 mi (7,233.18 km) |
| Middle Island to Ottaviano | 4,353.53 mi (7,006.33 km) |
| Middle Island to Ovada | 3,966.88 mi (6,384.07 km) |
| Middle Island to Ozieri | 4,116.97 mi (6,625.62 km) |
| Middle Island to Paceco | 4,372.22 mi (7,036.40 km) |
