| Middelharnis to Sestu | 892.11 mi (1,435.71 km) |
| Middelharnis to Settimo Torinese | 485.83 mi (781.87 km) |
| Middelharnis to Seveso | 478.63 mi (770.28 km) |
| Middelharnis to Sezze | 823.11 mi (1,324.67 km) |
| Middelharnis to Siano | 906.14 mi (1,458.29 km) |
| Middelharnis to Siena | 670.81 mi (1,079.57 km) |
| Middelharnis to Signa | 636.97 mi (1,025.10 km) |
| Middelharnis to Silea | 560.29 mi (901.70 km) |
| Middelharnis to Silvi Paese | 787.47 mi (1,267.31 km) |
| Middelharnis to Sinalunga | 686.43 mi (1,104.70 km) |
| Middelharnis to Siniscola | 815.60 mi (1,312.59 km) |
| Middelharnis to Sinnai | 893.32 mi (1,437.67 km) |
| Middelharnis to Siracusa | 1,150.27 mi (1,851.18 km) |
| Middelharnis to Solaro | 479.25 mi (771.27 km) |
| Middelharnis to Soliera | 575.04 mi (925.44 km) |
