| Michigan City to Superior (Colorado) | 962.29 mi (1,548.65 km) |
| Michigan City to Superior (Wisconsin) | 430.26 mi (692.44 km) |
| Michigan City to Surprise (Arizona) | 1,497.53 mi (2,410.05 km) |
| Michigan City to Susanville (California) | 1,748.85 mi (2,814.51 km) |
| Michigan City to Sussex (Wisconsin) | 120.27 mi (193.56 km) |
| Michigan City to Suwanee (Georgia) | 550.65 mi (886.19 km) |
| Michigan City to Swansea (Illinois) | 273.33 mi (439.89 km) |
| Michigan City to Sweetwater (Florida) | 1,161.28 mi (1,868.89 km) |
| Michigan City to Sweetwater (Texas) | 979.94 mi (1,577.06 km) |
| Michigan City to Sycamore (Illinois) | 95.39 mi (153.51 km) |
| Michigan City to Sylacauga (Alabama) | 590.39 mi (950.14 km) |
| Michigan City to Sylvania (Ohio) | 162.97 mi (262.28 km) |
| Michigan City to Syosset (New York) | 696.28 mi (1,120.55 km) |
| Michigan City to Syracuse (New York) | 554.72 mi (892.74 km) |
| Michigan City to Syracuse (Utah) | 1,302.19 mi (2,095.67 km) |
