| Michigan City to Scottsboro (Alabama) | 490.19 mi (788.89 km) |
| Michigan City to Scottsdale (Arizona) | 1,467.95 mi (2,362.44 km) |
| Michigan City to Scranton (Pennsylvania) | 579.25 mi (932.22 km) |
| Michigan City to Seabrook (Maryland) | 559.86 mi (901.01 km) |
| Michigan City to Seabrook (Texas) | 954.16 mi (1,535.57 km) |
| Michigan City to Seaford (New York) | 698.54 mi (1,124.19 km) |
| Michigan City to Seagoville (Texas) | 820.62 mi (1,320.66 km) |
| Michigan City to Seal Beach (California) | 1,780.14 mi (2,864.86 km) |
| Michigan City to Searcy (Arkansas) | 518.39 mi (834.27 km) |
| Michigan City to Seaside (California) | 1,891.57 mi (3,044.18 km) |
| Michigan City to SeaTac (Washington) | 1,771.79 mi (2,851.43 km) |
| Michigan City to Seattle (Washington) | 1,772.98 mi (2,853.34 km) |
| Michigan City to Sebastian (Florida) | 1,027.53 mi (1,653.64 km) |
| Michigan City to Sebring (Florida) | 1,029.88 mi (1,657.44 km) |
| Michigan City to Secaucus (New Jersey) | 667.59 mi (1,074.39 km) |
