| Michigan City to Sanford (Maine) | 827.05 mi (1,331.01 km) |
| Michigan City to Sanford (North Carolina) | 597.26 mi (961.20 km) |
| Michigan City to Sanger (California) | 1,772.94 mi (2,853.27 km) |
| Michigan City to Santa Ana (California) | 1,771.01 mi (2,850.16 km) |
| Michigan City to Santa Barbara (California) | 1,843.96 mi (2,967.57 km) |
| Michigan City to Santa Clara (California) | 1,880.91 mi (3,027.04 km) |
| Michigan City to Santa Clara (Oregon) | 1,827.78 mi (2,941.52 km) |
| Michigan City to Santa Clarita (California) | 1,781.46 mi (2,866.98 km) |
| Michigan City to Santa Cruz (California) | 1,893.71 mi (3,047.64 km) |
| Michigan City to Santa Fe (New Mexico) | 1,109.24 mi (1,785.15 km) |
| Michigan City to Santa Fe (Texas) | 967.74 mi (1,557.43 km) |
| Michigan City to Santa Fe Springs (California) | 1,774.08 mi (2,855.11 km) |
| Michigan City to Santa Maria (California) | 1,866.34 mi (3,003.58 km) |
| Michigan City to Santa Monica (California) | 1,792.69 mi (2,885.05 km) |
| Michigan City to Santa Paula (California) | 1,812.56 mi (2,917.04 km) |
