| Metairie to Southern Pines (North Carolina) | 721.97 mi (1,161.90 km) |
| Metairie to Southfield (Michigan) | 943.61 mi (1,518.60 km) |
| Metairie to Southgate (Michigan) | 928.07 mi (1,493.58 km) |
| Metairie to Southlake (Texas) | 458.70 mi (738.20 km) |
| Metairie to Spanaway (Washington) | 2,081.97 mi (3,350.60 km) |
| Metairie to Spanish Fork (Utah) | 1,395.20 mi (2,245.35 km) |
| Metairie to Spanish Lake (Missouri) | 607.38 mi (977.49 km) |
| Metairie to Spanish Springs (Nevada) | 1,790.65 mi (2,881.78 km) |
| Metairie to Sparks (Nevada) | 1,791.83 mi (2,883.66 km) |
| Metairie to Spartanburg (South Carolina) | 589.75 mi (949.11 km) |
| Metairie to Spearfish (South Dakota) | 1,247.48 mi (2,007.62 km) |
| Metairie to Speedway (Indiana) | 712.32 mi (1,146.37 km) |
| Metairie to Spencer (Iowa) | 949.06 mi (1,527.36 km) |
| Metairie to Spokane (Washington) | 1,890.95 mi (3,043.18 km) |
| Metairie to Spokane Valley (Washington) | 1,882.83 mi (3,030.13 km) |
