| Metairie to Enterprise (Nevada) | 1,504.95 mi (2,421.99 km) |
| Metairie to Enumclaw (Washington) | 2,066.10 mi (3,325.07 km) |
| Metairie to Ephrata (Pennsylvania) | 1,056.47 mi (1,700.22 km) |
| Metairie to Erie (Colorado) | 1,087.60 mi (1,750.33 km) |
| Metairie to Erie (Pennsylvania) | 1,008.14 mi (1,622.44 km) |
| Metairie to Erlanger (Kentucky) | 699.04 mi (1,124.99 km) |
| Metairie to Escanaba (Michigan) | 1,100.95 mi (1,771.80 km) |
| Metairie to Escondido (California) | 1,593.61 mi (2,564.66 km) |
| Metairie to Española (New Mexico) | 1,008.33 mi (1,622.75 km) |
| Metairie to Essex (Maryland) | 1,009.14 mi (1,624.06 km) |
| Metairie to Essex Junction (Vermont) | 1,366.85 mi (2,199.73 km) |
| Metairie to Estelle (Louisiana) | 11.51 mi (18.52 km) |
| Metairie to Estero (Florida) | 566.64 mi (911.93 km) |
| Metairie to Euclid (Ohio) | 935.33 mi (1,505.27 km) |
| Metairie to Eufaula (Alabama) | 325.84 mi (524.39 km) |
