| Mesquite to Silver Firs (Washington) | 1,690.23 mi (2,720.16 km) |
| Mesquite to Silver Spring (Maryland) | 1,174.17 mi (1,889.65 km) |
| Mesquite to Silver Springs Shores (Florida) | 898.71 mi (1,446.33 km) |
| Mesquite to Silverdale (Washington) | 1,705.60 mi (2,744.89 km) |
| Mesquite to Silverton (Oregon) | 1,632.28 mi (2,626.90 km) |
| Mesquite to Simi Valley (California) | 1,278.42 mi (2,057.42 km) |
| Mesquite to Simpsonville (South Carolina) | 833.68 mi (1,341.68 km) |
| Mesquite to Sioux City (Iowa) | 672.76 mi (1,082.70 km) |
| Mesquite to Sioux Falls (South Dakota) | 744.83 mi (1,198.68 km) |
| Mesquite to Skokie (Illinois) | 803.09 mi (1,292.44 km) |
| Mesquite to Sleepy Hollow (New York) | 1,374.96 mi (2,212.79 km) |
| Mesquite to Slidell (Louisiana) | 435.46 mi (700.81 km) |
| Mesquite to Smithfield (North Carolina) | 1,058.54 mi (1,703.56 km) |
| Mesquite to Smithfield (Utah) | 1,043.66 mi (1,679.61 km) |
| Mesquite to Smithville (Missouri) | 471.74 mi (759.19 km) |
