| Mesquite to Scottsboro (Alabama) | 619.21 mi (996.52 km) |
| Mesquite to Scottsdale (Arizona) | 884.60 mi (1,423.63 km) |
| Mesquite to Scranton (Pennsylvania) | 1,293.96 mi (2,082.43 km) |
| Mesquite to Seabrook (Maryland) | 1,182.59 mi (1,903.19 km) |
| Mesquite to Seabrook (Texas) | 238.67 mi (384.11 km) |
| Mesquite to Seaford (New York) | 1,385.55 mi (2,229.83 km) |
| Mesquite to Seagoville (Texas) | 7.78 mi (12.52 km) |
| Mesquite to Seal Beach (California) | 1,240.99 mi (1,997.18 km) |
| Mesquite to Searcy (Arkansas) | 326.46 mi (525.39 km) |
| Mesquite to Seaside (California) | 1,453.76 mi (2,339.60 km) |
| Mesquite to SeaTac (Washington) | 1,682.61 mi (2,707.89 km) |
| Mesquite to Seattle (Washington) | 1,689.39 mi (2,718.81 km) |
| Mesquite to Sebastian (Florida) | 1,019.36 mi (1,640.50 km) |
| Mesquite to Sebring (Florida) | 974.12 mi (1,567.70 km) |
| Mesquite to Secaucus (New Jersey) | 1,358.93 mi (2,186.99 km) |
