| Mesquite to Sanford (Maine) | 1,576.87 mi (2,537.73 km) |
| Mesquite to Sanford (North Carolina) | 1,012.04 mi (1,628.72 km) |
| Mesquite to Sanger (California) | 1,329.06 mi (2,138.91 km) |
| Mesquite to Santa Ana (California) | 1,230.18 mi (1,979.78 km) |
| Mesquite to Santa Barbara (California) | 1,333.50 mi (2,146.06 km) |
| Mesquite to Santa Clara (California) | 1,465.51 mi (2,358.51 km) |
| Mesquite to Santa Clara (Oregon) | 1,626.60 mi (2,617.76 km) |
| Mesquite to Santa Clarita (California) | 1,263.78 mi (2,033.86 km) |
| Mesquite to Santa Cruz (California) | 1,467.12 mi (2,361.10 km) |
| Mesquite to Santa Fe (New Mexico) | 572.75 mi (921.74 km) |
| Mesquite to Santa Fe (Texas) | 248.98 mi (400.69 km) |
| Mesquite to Santa Fe Springs (California) | 1,239.94 mi (1,995.48 km) |
| Mesquite to Santa Maria (California) | 1,373.92 mi (2,211.11 km) |
| Mesquite to Santa Monica (California) | 1,263.65 mi (2,033.66 km) |
| Mesquite to Santa Paula (California) | 1,296.32 mi (2,086.23 km) |
