| Mesquite to Olympia Heights (Florida) | 1,091.77 mi (1,757.04 km) |
| Mesquite to Omaha (Nebraska) | 588.20 mi (946.62 km) |
| Mesquite to On Top of the World Designated Place (Florida) | 883.47 mi (1,421.80 km) |
| Mesquite to Onalaska (Wisconsin) | 821.82 mi (1,322.59 km) |
| Mesquite to Oneida (New York) | 1,339.19 mi (2,155.23 km) |
| Mesquite to Oneonta (New York) | 1,349.39 mi (2,171.63 km) |
| Mesquite to Ontario (California) | 1,213.57 mi (1,953.05 km) |
| Mesquite to Ontario (Oregon) | 1,344.88 mi (2,164.37 km) |
| Mesquite to Opa-locka (Florida) | 1,090.23 mi (1,754.56 km) |
| Mesquite to Opelika (Alabama) | 651.41 mi (1,048.34 km) |
| Mesquite to Opelousas (Louisiana) | 306.65 mi (493.51 km) |
| Mesquite to Orange (California) | 1,226.51 mi (1,973.88 km) |
| Mesquite to Orange (Texas) | 246.88 mi (397.31 km) |
| Mesquite to Orange City (Florida) | 944.17 mi (1,519.50 km) |
| Mesquite to Orangeburg (South Carolina) | 910.11 mi (1,464.69 km) |
