| Mercer Island to Enterprise (Nevada) | 875.36 mi (1,408.75 km) |
| Mercer Island to Enumclaw (Washington) | 27.61 mi (44.43 km) |
| Mercer Island to Ephrata (Pennsylvania) | 2,314.02 mi (3,724.06 km) |
| Mercer Island to Erie (Colorado) | 999.36 mi (1,608.31 km) |
| Mercer Island to Erie (Pennsylvania) | 2,073.05 mi (3,336.26 km) |
| Mercer Island to Erlanger (Kentucky) | 1,961.67 mi (3,157.01 km) |
| Mercer Island to Escanaba (Michigan) | 1,656.98 mi (2,666.66 km) |
| Mercer Island to Escondido (California) | 1,032.85 mi (1,662.21 km) |
| Mercer Island to Española (New Mexico) | 1,149.57 mi (1,850.06 km) |
| Mercer Island to Essex (Maryland) | 2,331.09 mi (3,751.53 km) |
| Mercer Island to Essex Junction (Vermont) | 2,326.27 mi (3,743.77 km) |
| Mercer Island to Estelle (Louisiana) | 2,097.31 mi (3,375.29 km) |
| Mercer Island to Estero (Florida) | 2,623.21 mi (4,221.65 km) |
| Mercer Island to Euclid (Ohio) | 2,021.48 mi (3,253.26 km) |
| Mercer Island to Eufaula (Alabama) | 2,218.26 mi (3,569.94 km) |
