| Mendrisio to Scottsboro (Alabama) | 4,770.04 mi (7,676.64 km) |
| Mendrisio to Scottsdale (Arizona) | 5,817.91 mi (9,363.02 km) |
| Mendrisio to Scranton (Pennsylvania) | 4,037.80 mi (6,498.21 km) |
| Mendrisio to Seabrook (Maryland) | 4,187.47 mi (6,739.08 km) |
| Mendrisio to Seabrook (Texas) | 5,390.29 mi (8,674.83 km) |
| Mendrisio to Seaford (New York) | 3,974.82 mi (6,396.86 km) |
| Mendrisio to Seagoville (Texas) | 5,298.50 mi (8,527.11 km) |
| Mendrisio to Seal Beach (California) | 6,020.67 mi (9,689.33 km) |
| Mendrisio to Searcy (Arkansas) | 4,977.39 mi (8,010.33 km) |
| Mendrisio to Seaside (California) | 5,969.02 mi (9,606.21 km) |
| Mendrisio to SeaTac (Washington) | 5,348.46 mi (8,607.52 km) |
| Mendrisio to Seattle (Washington) | 5,338.80 mi (8,591.97 km) |
| Mendrisio to Sebastian (Florida) | 4,843.82 mi (7,795.38 km) |
| Mendrisio to Sebring (Florida) | 4,901.94 mi (7,888.92 km) |
| Mendrisio to Secaucus (New Jersey) | 3,994.87 mi (6,429.13 km) |
