| Memphis to Southern Pines (North Carolina) | 596.45 mi (959.90 km) |
| Memphis to Southfield (Michigan) | 623.68 mi (1,003.71 km) |
| Memphis to Southgate (Michigan) | 610.64 mi (982.73 km) |
| Memphis to Southlake (Texas) | 437.32 mi (703.80 km) |
| Memphis to Spanaway (Washington) | 1,863.86 mi (2,999.59 km) |
| Memphis to Spanish Fork (Utah) | 1,232.08 mi (1,982.84 km) |
| Memphis to Spanish Lake (Missouri) | 254.59 mi (409.73 km) |
| Memphis to Spanish Springs (Nevada) | 1,652.86 mi (2,660.03 km) |
| Memphis to Sparks (Nevada) | 1,655.21 mi (2,663.80 km) |
| Memphis to Spartanburg (South Carolina) | 454.99 mi (732.23 km) |
| Memphis to Spearfish (South Dakota) | 977.69 mi (1,573.44 km) |
| Memphis to Speedway (Indiana) | 382.50 mi (615.58 km) |
| Memphis to Spencer (Iowa) | 620.76 mi (999.01 km) |
| Memphis to Spokane (Washington) | 1,654.05 mi (2,661.94 km) |
| Memphis to Spokane Valley (Washington) | 1,645.36 mi (2,647.95 km) |
