| Melville to Southern Pines (North Carolina) | 505.43 mi (813.42 km) |
| Melville to Southfield (Michigan) | 521.74 mi (839.67 km) |
| Melville to Southgate (Michigan) | 516.15 mi (830.66 km) |
| Melville to Southlake (Texas) | 1,413.71 mi (2,275.14 km) |
| Melville to Spanaway (Washington) | 2,436.20 mi (3,920.68 km) |
| Melville to Spanish Fork (Utah) | 1,994.70 mi (3,210.15 km) |
| Melville to Spanish Lake (Missouri) | 901.07 mi (1,450.13 km) |
| Melville to Spanish Springs (Nevada) | 2,413.12 mi (3,883.55 km) |
| Melville to Sparks (Nevada) | 2,417.20 mi (3,890.10 km) |
| Melville to Spartanburg (South Carolina) | 614.69 mi (989.24 km) |
| Melville to Spearfish (South Dakota) | 1,557.38 mi (2,506.37 km) |
| Melville to Speedway (Indiana) | 679.51 mi (1,093.57 km) |
| Melville to Spencer (Iowa) | 1,125.75 mi (1,811.72 km) |
| Melville to Spokane (Washington) | 2,199.93 mi (3,540.45 km) |
| Melville to Spokane Valley (Washington) | 2,190.74 mi (3,525.66 km) |
