| Melsungen to Southern Pines (North Carolina) | 4,334.62 mi (6,975.89 km) |
| Melsungen to Southfield (Michigan) | 4,131.45 mi (6,648.93 km) |
| Melsungen to Southgate (Michigan) | 4,142.37 mi (6,666.50 km) |
| Melsungen to Southlake (Texas) | 5,126.93 mi (8,250.99 km) |
| Melsungen to Spanaway (Washington) | 5,075.71 mi (8,168.57 km) |
| Melsungen to Spanish Fork (Utah) | 5,205.51 mi (8,377.45 km) |
| Melsungen to Spanish Lake (Missouri) | 4,568.29 mi (7,351.96 km) |
| Melsungen to Spanish Springs (Nevada) | 5,455.86 mi (8,780.35 km) |
| Melsungen to Sparks (Nevada) | 5,462.08 mi (8,790.37 km) |
| Melsungen to Spartanburg (South Carolina) | 4,446.79 mi (7,156.41 km) |
| Melsungen to Spearfish (South Dakota) | 4,726.03 mi (7,605.81 km) |
| Melsungen to Speedway (Indiana) | 4,372.27 mi (7,036.49 km) |
| Melsungen to Spencer (Iowa) | 4,518.79 mi (7,272.29 km) |
| Melsungen to Spokane (Washington) | 4,923.22 mi (7,923.16 km) |
| Melsungen to Spokane Valley (Washington) | 4,918.59 mi (7,915.71 km) |
