| Melbourne to Southern Pines (North Carolina) | 495.02 mi (796.65 km) |
| Melbourne to Southfield (Michigan) | 1,003.34 mi (1,614.71 km) |
| Melbourne to Southgate (Michigan) | 984.35 mi (1,584.16 km) |
| Melbourne to Southlake (Texas) | 1,035.39 mi (1,666.29 km) |
| Melbourne to Spanaway (Washington) | 2,593.14 mi (4,173.26 km) |
| Melbourne to Spanish Fork (Utah) | 1,943.25 mi (3,127.36 km) |
| Melbourne to Spanish Lake (Missouri) | 919.27 mi (1,479.42 km) |
| Melbourne to Spanish Springs (Nevada) | 2,353.88 mi (3,788.21 km) |
| Melbourne to Sparks (Nevada) | 2,355.59 mi (3,790.96 km) |
| Melbourne to Spartanburg (South Carolina) | 478.10 mi (769.42 km) |
| Melbourne to Spearfish (South Dakota) | 1,704.57 mi (2,743.24 km) |
| Melbourne to Speedway (Indiana) | 868.01 mi (1,396.93 km) |
| Melbourne to Spencer (Iowa) | 1,315.66 mi (2,117.36 km) |
| Melbourne to Spokane (Washington) | 2,383.78 mi (3,836.33 km) |
| Melbourne to Spokane Valley (Washington) | 2,375.07 mi (3,822.31 km) |
