| Melbourne to Silver Firs (Washington) | 2,595.40 mi (4,176.90 km) |
| Melbourne to Silver Spring (Maryland) | 781.18 mi (1,257.19 km) |
| Melbourne to Silver Springs Shores (Florida) | 107.42 mi (172.88 km) |
| Melbourne to Silverdale (Washington) | 2,615.38 mi (4,209.05 km) |
| Melbourne to Silverton (Oregon) | 2,575.13 mi (4,144.28 km) |
| Melbourne to Simi Valley (California) | 2,277.52 mi (3,665.31 km) |
| Melbourne to Simpsonville (South Carolina) | 466.94 mi (751.47 km) |
| Melbourne to Sioux City (Iowa) | 1,327.63 mi (2,136.61 km) |
| Melbourne to Sioux Falls (South Dakota) | 1,390.19 mi (2,237.29 km) |
| Melbourne to Skokie (Illinois) | 1,041.22 mi (1,675.68 km) |
| Melbourne to Sleepy Hollow (New York) | 975.94 mi (1,570.62 km) |
| Melbourne to Slidell (Louisiana) | 570.12 mi (917.53 km) |
| Melbourne to Smithfield (North Carolina) | 529.28 mi (851.80 km) |
| Melbourne to Smithfield (Utah) | 1,987.46 mi (3,198.51 km) |
| Melbourne to Smithville (Missouri) | 1,113.88 mi (1,792.62 km) |
