| McDonough to University Place (Washington) | 2,206.41 mi (3,550.88 km) |
| McDonough to Upland (California) | 1,916.34 mi (3,084.05 km) |
| McDonough to Upper Arlington (Ohio) | 459.05 mi (738.77 km) |
| McDonough to Upper Grand Lagoon (Florida) | 244.50 mi (393.49 km) |
| McDonough to Upper Montclair (New Jersey) | 748.72 mi (1,204.95 km) |
| McDonough to Urbana (Illinois) | 512.30 mi (824.46 km) |
| McDonough to Urbana (Maryland) | 555.44 mi (893.89 km) |
| McDonough to Urbana (Ohio) | 461.29 mi (742.37 km) |
| McDonough to Urbandale (Iowa) | 773.16 mi (1,244.28 km) |
| McDonough to Utica (New York) | 823.26 mi (1,324.90 km) |
| McDonough to Uvalde (Texas) | 966.27 mi (1,555.06 km) |
| McDonough to Vacaville (California) | 2,128.62 mi (3,425.68 km) |
| McDonough to Vadnais Heights (Minnesota) | 932.61 mi (1,500.90 km) |
| McDonough to Vail (Arizona) | 1,541.70 mi (2,481.13 km) |
| McDonough to Valdosta (Georgia) | 186.04 mi (299.40 km) |
