| McDonough to Superior (Colorado) | 1,243.75 mi (2,001.62 km) |
| McDonough to Superior (Wisconsin) | 1,005.98 mi (1,618.97 km) |
| McDonough to Surprise (Arizona) | 1,624.38 mi (2,614.19 km) |
| McDonough to Susanville (California) | 2,055.31 mi (3,307.70 km) |
| McDonough to Sussex (Wisconsin) | 705.07 mi (1,134.71 km) |
| McDonough to Suwanee (Georgia) | 42.48 mi (68.37 km) |
| McDonough to Swansea (Illinois) | 480.52 mi (773.32 km) |
| McDonough to Sweetwater (Florida) | 575.72 mi (926.53 km) |
| McDonough to Sweetwater (Texas) | 944.04 mi (1,519.28 km) |
| McDonough to Sycamore (Illinois) | 640.69 mi (1,031.09 km) |
| McDonough to Sylacauga (Alabama) | 123.17 mi (198.22 km) |
| McDonough to Sylvania (Ohio) | 571.93 mi (920.43 km) |
| McDonough to Syosset (New York) | 776.00 mi (1,248.84 km) |
| McDonough to Syracuse (New York) | 792.13 mi (1,274.81 km) |
| McDonough to Syracuse (Utah) | 1,615.31 mi (2,599.58 km) |
