| McDonough to Storm Lake (Iowa) | 873.49 mi (1,405.75 km) |
| McDonough to Storrs (Connecticut) | 869.30 mi (1,399.00 km) |
| McDonough to Stoughton (Wisconsin) | 710.46 mi (1,143.38 km) |
| McDonough to Stow (Ohio) | 554.92 mi (893.06 km) |
| McDonough to Streamwood (Illinois) | 632.23 mi (1,017.47 km) |
| McDonough to Streator (Illinois) | 589.76 mi (949.12 km) |
| McDonough to Streetsboro (Ohio) | 560.42 mi (901.91 km) |
| McDonough to Strongsville (Ohio) | 558.62 mi (899.01 km) |
| McDonough to Stuart (Florida) | 490.18 mi (788.86 km) |
| McDonough to Stuarts Draft (Virginia) | 426.94 mi (687.10 km) |
| McDonough to Sturgis (Michigan) | 581.71 mi (936.17 km) |
| McDonough to Suamico (Wisconsin) | 801.35 mi (1,289.64 km) |
| McDonough to Sudley (Virginia) | 523.63 mi (842.70 km) |
| McDonough to Suffern (New York) | 763.14 mi (1,228.16 km) |
| McDonough to Suffolk (Virginia) | 480.41 mi (773.15 km) |
