| McDonough to Scottsboro (Alabama) | 136.88 mi (220.29 km) |
| McDonough to Scottsdale (Arizona) | 1,590.89 mi (2,560.29 km) |
| McDonough to Scranton (Pennsylvania) | 720.09 mi (1,158.88 km) |
| McDonough to Seabrook (Maryland) | 558.36 mi (898.59 km) |
| McDonough to Seabrook (Texas) | 693.45 mi (1,115.99 km) |
| McDonough to Seaford (New York) | 770.20 mi (1,239.52 km) |
| McDonough to Seagoville (Texas) | 719.50 mi (1,157.93 km) |
| McDonough to Seal Beach (California) | 1,943.37 mi (3,127.56 km) |
| McDonough to Searcy (Arkansas) | 450.12 mi (724.40 km) |
| McDonough to Seaside (California) | 2,128.90 mi (3,426.14 km) |
| McDonough to SeaTac (Washington) | 2,198.32 mi (3,537.85 km) |
| McDonough to Seattle (Washington) | 2,202.09 mi (3,543.91 km) |
| McDonough to Sebastian (Florida) | 447.56 mi (720.27 km) |
| McDonough to Sebring (Florida) | 442.14 mi (711.56 km) |
| McDonough to Secaucus (New Jersey) | 751.40 mi (1,209.27 km) |
