| McDonough to Elyria (Ohio) | 559.66 mi (900.68 km) |
| McDonough to Emeryville (California) | 2,148.26 mi (3,457.28 km) |
| McDonough to Emmaus (Pennsylvania) | 683.70 mi (1,100.31 km) |
| McDonough to Emporia (Kansas) | 755.20 mi (1,215.38 km) |
| McDonough to Encinitas (California) | 1,905.31 mi (3,066.29 km) |
| McDonough to Endicott (New York) | 742.82 mi (1,195.46 km) |
| McDonough to Endwell (New York) | 745.28 mi (1,199.41 km) |
| McDonough to Englewood (Colorado) | 1,230.41 mi (1,980.16 km) |
| McDonough to Englewood (Florida) | 459.59 mi (739.63 km) |
| McDonough to Englewood (New Jersey) | 759.98 mi (1,223.08 km) |
| McDonough to Englewood (Ohio) | 443.98 mi (714.52 km) |
| McDonough to Enid (Oklahoma) | 803.00 mi (1,292.31 km) |
| McDonough to Ennis (Texas) | 728.01 mi (1,171.62 km) |
| McDonough to Ensley (Florida) | 272.04 mi (437.81 km) |
| McDonough to Enterprise (Alabama) | 176.31 mi (283.75 km) |
