| McAllen to Enterprise (Nevada) | 1,207.80 mi (1,943.77 km) |
| McAllen to Enumclaw (Washington) | 1,941.41 mi (3,124.39 km) |
| McAllen to Ephrata (Pennsylvania) | 1,591.40 mi (2,561.11 km) |
| McAllen to Erie (Colorado) | 1,031.44 mi (1,659.94 km) |
| McAllen to Erie (Pennsylvania) | 1,505.14 mi (2,422.29 km) |
| McAllen to Erlanger (Kentucky) | 1,185.60 mi (1,908.04 km) |
| McAllen to Escanaba (Michigan) | 1,482.67 mi (2,386.12 km) |
| McAllen to Escondido (California) | 1,224.37 mi (1,970.43 km) |
| McAllen to Española (New Mexico) | 818.19 mi (1,316.76 km) |
| McAllen to Essex (Maryland) | 1,549.03 mi (2,492.93 km) |
| McAllen to Essex Junction (Vermont) | 1,882.66 mi (3,029.85 km) |
| McAllen to Estelle (Louisiana) | 555.89 mi (894.62 km) |
| McAllen to Estero (Florida) | 1,018.20 mi (1,638.64 km) |
| McAllen to Euclid (Ohio) | 1,425.51 mi (2,294.13 km) |
| McAllen to Eufaula (Alabama) | 882.13 mi (1,419.66 km) |
