| Mason City to Southern Pines (North Carolina) | 919.02 mi (1,479.01 km) |
| Mason City to Southfield (Michigan) | 505.61 mi (813.70 km) |
| Mason City to Southgate (Michigan) | 511.52 mi (823.21 km) |
| Mason City to Southlake (Texas) | 736.18 mi (1,184.76 km) |
| Mason City to Spanaway (Washington) | 1,441.76 mi (2,320.28 km) |
| Mason City to Spanish Fork (Utah) | 973.08 mi (1,566.02 km) |
| Mason City to Spanish Lake (Missouri) | 339.24 mi (545.96 km) |
| Mason City to Spanish Springs (Nevada) | 1,386.85 mi (2,231.92 km) |
| Mason City to Sparks (Nevada) | 1,391.05 mi (2,238.68 km) |
| Mason City to Spartanburg (South Carolina) | 827.67 mi (1,332.01 km) |
| Mason City to Spearfish (South Dakota) | 536.88 mi (864.03 km) |
| Mason City to Speedway (Indiana) | 427.86 mi (688.57 km) |
| Mason City to Spencer (Iowa) | 98.48 mi (158.49 km) |
| Mason City to Spokane (Washington) | 1,210.71 mi (1,948.45 km) |
| Mason City to Spokane Valley (Washington) | 1,201.50 mi (1,933.62 km) |
