| Tampa (Florida) to Weslaco | 963.90 mi (1,551.24 km) |
| Atlanta (Georgia) to Weslaco | 965.74 mi (1,554.21 km) |
| St. Louis (Missouri) to Weslaco | 972.22 mi (1,564.64 km) |
| Phoenix (Arizona) to Weslaco | 986.56 mi (1,587.71 km) |
| Denver (Colorado) to Weslaco | 1,020.27 mi (1,641.96 km) |
| Miami (Florida) to Weslaco | 1,103.71 mi (1,776.25 km) |
| Chicago (Illinois) to Weslaco | 1,231.29 mi (1,981.57 km) |
| Las Vegas (Nevada) to Weslaco | 1,232.63 mi (1,983.73 km) |
| San Diego (California) to Weslaco | 1,237.21 mi (1,991.09 km) |
| Riverside (California) to Weslaco | 1,276.17 mi (2,053.79 km) |
| Minneapolis (Minnesota) to Weslaco | 1,325.40 mi (2,133.02 km) |
| Los Angeles (California) to Weslaco | 1,334.88 mi (2,148.28 km) |
| Detroit (Michigan) to Weslaco | 1,402.12 mi (2,256.49 km) |
| Washington (District of Columbia) to Weslaco | 1,499.73 mi (2,413.59 km) |
| Baltimore (Maryland) to Weslaco | 1,532.18 mi (2,465.81 km) |
| Philadelphia (Pennsylvania) to Weslaco | 1,624.63 mi (2,614.59 km) |
| San Francisco (California) to Weslaco | 1,635.03 mi (2,631.33 km) |
| Brooklyn (New York) to Weslaco | 1,700.69 mi (2,736.99 km) |
| New York (New York) to Weslaco | 1,703.29 mi (2,741.18 km) |
| Queens (New York) to Weslaco | 1,710.98 mi (2,753.55 km) |
| Boston (Massachusetts) to Weslaco | 1,885.79 mi (3,034.89 km) |
| Portland (Oregon) to Weslaco | 1,908.66 mi (3,071.69 km) |
| Seattle (Washington) to Weslaco | 1,984.96 mi (3,194.48 km) |
| Houston (Texas) to Weslaco | 296.50 mi (477.16 km) |
| Dallas (Texas) to Weslaco | 464.17 mi (747.01 km) |
