| Manhattan to Storm Lake (Iowa) | 1,099.55 mi (1,769.55 km) |
| Manhattan to Storrs (Connecticut) | 113.74 mi (183.05 km) |
| Manhattan to Stoughton (Wisconsin) | 797.79 mi (1,283.92 km) |
| Manhattan to Stow (Ohio) | 390.38 mi (628.25 km) |
| Manhattan to Streamwood (Illinois) | 740.61 mi (1,191.90 km) |
| Manhattan to Streator (Illinois) | 775.02 mi (1,247.28 km) |
| Manhattan to Streetsboro (Ohio) | 385.91 mi (621.06 km) |
| Manhattan to Strongsville (Ohio) | 411.32 mi (661.95 km) |
| Manhattan to Stuart (Florida) | 1,004.61 mi (1,616.76 km) |
| Manhattan to Stuarts Draft (Virginia) | 331.17 mi (532.96 km) |
| Manhattan to Sturgis (Michigan) | 598.21 mi (962.72 km) |
| Manhattan to Suamico (Wisconsin) | 762.60 mi (1,227.29 km) |
| Manhattan to Sudley (Virginia) | 232.64 mi (374.40 km) |
| Manhattan to Suffern (New York) | 24.61 mi (39.60 km) |
| Manhattan to Suffolk (Virginia) | 317.05 mi (510.24 km) |
