| Manhattan to Savannah (Georgia) | 725.27 mi (1,167.21 km) |
| Manhattan to Sayreville (New Jersey) | 28.87 mi (46.47 km) |
| Manhattan to Sayville (New York) | 46.23 mi (74.40 km) |
| Manhattan to Scaggsville (Maryland) | 191.68 mi (308.48 km) |
| Manhattan to Scarsdale (New York) | 17.36 mi (27.95 km) |
| Manhattan to Schaumburg (Illinois) | 735.81 mi (1,184.17 km) |
| Manhattan to Schenectady (New York) | 139.52 mi (224.54 km) |
| Manhattan to Schererville (Indiana) | 702.34 mi (1,130.31 km) |
| Manhattan to Schertz (Texas) | 1,567.75 mi (2,523.05 km) |
| Manhattan to Schiller Park (Illinois) | 724.63 mi (1,166.18 km) |
| Manhattan to Schofield Barracks (Hawaii) | 4,963.10 mi (7,987.34 km) |
| Manhattan to Scotchtown (New York) | 52.23 mi (84.06 km) |
| Manhattan to Scottdale (Georgia) | 743.06 mi (1,195.84 km) |
| Manhattan to Scotts Valley (California) | 2,563.31 mi (4,125.25 km) |
| Manhattan to Scottsbluff (Nebraska) | 1,534.93 mi (2,470.23 km) |
