| Manhattan to Santa Rosa (California) | 2,565.71 mi (4,129.12 km) |
| Manhattan to Santaquin (Utah) | 1,976.29 mi (3,180.53 km) |
| Manhattan to Santee (California) | 2,416.40 mi (3,888.82 km) |
| Manhattan to Sapulpa (Oklahoma) | 1,239.38 mi (1,994.59 km) |
| Manhattan to Saraland (Alabama) | 1,045.58 mi (1,682.70 km) |
| Manhattan to Sarasota (Florida) | 1,049.37 mi (1,688.80 km) |
| Manhattan to Sarasota Springs (Florida) | 1,049.44 mi (1,688.90 km) |
| Manhattan to Saratoga (California) | 2,558.82 mi (4,118.02 km) |
| Manhattan to Saratoga Springs (New York) | 158.11 mi (254.45 km) |
| Manhattan to Saratoga Springs (Utah) | 1,976.36 mi (3,180.65 km) |
| Manhattan to Sartell (Minnesota) | 1,070.02 mi (1,722.02 km) |
| Manhattan to Satellite Beach (Florida) | 948.64 mi (1,526.69 km) |
| Manhattan to Sauk Rapids (Minnesota) | 1,066.57 mi (1,716.48 km) |
| Manhattan to Sault Ste. Marie (Michigan) | 651.64 mi (1,048.71 km) |
| Manhattan to Savage (Minnesota) | 1,018.61 mi (1,639.29 km) |
