| Manhattan to San Luis Obispo (California) | 2,540.11 mi (4,087.91 km) |
| Manhattan to San Marcos (California) | 2,417.98 mi (3,891.36 km) |
| Manhattan to San Marcos (Texas) | 1,539.79 mi (2,478.06 km) |
| Manhattan to San Marino (California) | 2,438.53 mi (3,924.43 km) |
| Manhattan to San Mateo (California) | 2,566.60 mi (4,130.54 km) |
| Manhattan to San Pablo (California) | 2,558.36 mi (4,117.28 km) |
| Manhattan to San Rafael (California) | 2,566.89 mi (4,131.01 km) |
| Manhattan to San Ramon (California) | 2,542.29 mi (4,091.42 km) |
| Manhattan to San Tan Valley (Arizona) | 2,123.18 mi (3,416.93 km) |
| Manhattan to Sand Springs (Oklahoma) | 1,237.57 mi (1,991.68 km) |
| Manhattan to Sandusky (Ohio) | 456.86 mi (735.25 km) |
| Manhattan to Sandy (Oregon) | 2,421.07 mi (3,896.33 km) |
| Manhattan to Sandy (Utah) | 1,969.47 mi (3,169.56 km) |
| Manhattan to Sandy Springs (Georgia) | 740.85 mi (1,192.28 km) |
| Manhattan to Sanford (Florida) | 925.86 mi (1,490.02 km) |
