| Manhattan to San Diego (California) | 2,424.30 mi (3,901.53 km) |
| Manhattan to San Diego Country Estates (California) | 2,401.47 mi (3,864.79 km) |
| Manhattan to San Dimas (California) | 2,423.05 mi (3,899.51 km) |
| Manhattan to San Fernando (California) | 2,450.72 mi (3,944.05 km) |
| Manhattan to San Francisco (California) | 2,568.51 mi (4,133.62 km) |
| Manhattan to San Gabriel (California) | 2,438.56 mi (3,924.49 km) |
| Manhattan to San Germán (Puerto Rico) | 1,621.41 mi (2,609.41 km) |
| Manhattan to San Jacinto (California) | 2,389.18 mi (3,845.01 km) |
| Manhattan to San Jose (California) | 2,548.85 mi (4,101.97 km) |
| Manhattan to San Juan (Puerto Rico) | 1,616.14 mi (2,600.93 km) |
| Manhattan to San Juan (Texas) | 1,710.48 mi (2,752.75 km) |
| Manhattan to San Juan Capistrano (California) | 2,432.36 mi (3,914.51 km) |
| Manhattan to San Leandro (California) | 2,555.06 mi (4,111.97 km) |
| Manhattan to San Lorenzo (California) | 2,554.51 mi (4,111.08 km) |
| Manhattan to San Luis (Arizona) | 2,308.32 mi (3,714.89 km) |
