| Manhattan to Oswego (Illinois) | 748.43 mi (1,204.48 km) |
| Manhattan to Oswego (New York) | 225.49 mi (362.89 km) |
| Manhattan to Otsego (Minnesota) | 1,036.89 mi (1,668.71 km) |
| Manhattan to Ottawa (Illinois) | 774.12 mi (1,245.82 km) |
| Manhattan to Ottawa (Kansas) | 1,139.46 mi (1,833.79 km) |
| Manhattan to Ottumwa (Iowa) | 961.99 mi (1,548.17 km) |
| Manhattan to Overland (Missouri) | 881.96 mi (1,419.38 km) |
| Manhattan to Overland Park (Kansas) | 1,104.53 mi (1,777.57 km) |
| Manhattan to Overlea (Maryland) | 166.75 mi (268.36 km) |
| Manhattan to Oviedo (Florida) | 931.90 mi (1,499.75 km) |
| Manhattan to Owasso (Oklahoma) | 1,218.29 mi (1,960.65 km) |
| Manhattan to Owatonna (Minnesota) | 1,006.07 mi (1,619.11 km) |
| Manhattan to Owensboro (Kentucky) | 733.02 mi (1,179.69 km) |
| Manhattan to Owings Mills (Maryland) | 176.85 mi (284.61 km) |
| Manhattan to Owosso (Michigan) | 546.53 mi (879.56 km) |
