| Manhattan to Indianapolis (Indiana) | 645.22 mi (1,038.38 km) |
| Manhattan to Indianola (Iowa) | 1,019.47 mi (1,640.68 km) |
| Manhattan to Indio (California) | 2,351.39 mi (3,784.20 km) |
| Manhattan to Inglewood (California) | 2,455.30 mi (3,951.42 km) |
| Manhattan to Inkster (Michigan) | 494.34 mi (795.56 km) |
| Manhattan to Inver Grove Heights (Minnesota) | 1,004.68 mi (1,616.87 km) |
| Manhattan to Inwood (New York) | 15.88 mi (25.55 km) |
| Manhattan to Iona (Florida) | 1,086.51 mi (1,748.57 km) |
| Manhattan to Ionia (Michigan) | 590.61 mi (950.50 km) |
| Manhattan to Iowa City (Iowa) | 913.23 mi (1,469.70 km) |
| Manhattan to Irmo (South Carolina) | 608.14 mi (978.71 km) |
| Manhattan to Irondale (Alabama) | 858.05 mi (1,380.91 km) |
| Manhattan to Ironton (Ohio) | 488.55 mi (786.24 km) |
| Manhattan to Irvine (California) | 2,433.50 mi (3,916.34 km) |
| Manhattan to Irving (Texas) | 1,379.82 mi (2,220.61 km) |
