| Manchester to Sunbury | 161.45 mi (259.82 km) |
| Manchester to Sunderland | 104.58 mi (168.30 km) |
| Manchester to Sunninghill | 158.35 mi (254.84 km) |
| Manchester to Surbiton | 165.60 mi (266.50 km) |
| Manchester to Sutton | 169.64 mi (273.01 km) |
| Manchester to Sutton Coldfield | 65.72 mi (105.76 km) |
| Manchester to Sutton in Ashfield | 47.45 mi (76.36 km) |
| Manchester to Sutton on Hull | 82.19 mi (132.27 km) |
| Manchester to Swadlincote | 56.48 mi (90.89 km) |
| Manchester to Swallownest | 38.74 mi (62.35 km) |
| Manchester to Swanage | 198.76 mi (319.88 km) |
| Manchester to Swindon | 134.05 mi (215.74 km) |
| Manchester to Swinton | 38.26 mi (61.57 km) |
| Manchester to Swinton | 4.55 mi (7.32 km) |
| Manchester to Syston | 72.37 mi (116.47 km) |
