| Lyons to Storm Lake (Iowa) | 381.64 mi (614.18 km) |
| Lyons to Storrs (Connecticut) | 800.63 mi (1,288.48 km) |
| Lyons to Stoughton (Wisconsin) | 105.04 mi (169.04 km) |
| Lyons to Stow (Ohio) | 333.25 mi (536.31 km) |
| Lyons to Streamwood (Illinois) | 23.43 mi (37.70 km) |
| Lyons to Streator (Illinois) | 70.66 mi (113.72 km) |
| Lyons to Streetsboro (Ohio) | 337.10 mi (542.51 km) |
| Lyons to Strongsville (Ohio) | 311.41 mi (501.16 km) |
| Lyons to Stuart (Florida) | 1,096.96 mi (1,765.38 km) |
| Lyons to Stuarts Draft (Virginia) | 533.80 mi (859.06 km) |
| Lyons to Sturgis (Michigan) | 123.64 mi (198.98 km) |
| Lyons to Suamico (Wisconsin) | 195.49 mi (314.61 km) |
| Lyons to Sudley (Virginia) | 582.25 mi (937.04 km) |
| Lyons to Suffern (New York) | 709.04 mi (1,141.10 km) |
| Lyons to Suffolk (Virginia) | 693.94 mi (1,116.79 km) |
