| Lyons to Stephenville (Texas) | 875.55 mi (1,409.07 km) |
| Lyons to Sterling (Colorado) | 802.16 mi (1,290.95 km) |
| Lyons to Sterling (Illinois) | 96.65 mi (155.54 km) |
| Lyons to Sterling (Virginia) | 580.73 mi (934.60 km) |
| Lyons to Sterling Heights (Michigan) | 250.77 mi (403.58 km) |
| Lyons to Steubenville (Ohio) | 386.25 mi (621.61 km) |
| Lyons to Stevens Point (Wisconsin) | 206.70 mi (332.66 km) |
| Lyons to Stevenson Ranch (California) | 1,739.16 mi (2,798.91 km) |
| Lyons to Stillwater (Minnesota) | 336.81 mi (542.04 km) |
| Lyons to Stillwater (Oklahoma) | 632.75 mi (1,018.32 km) |
| Lyons to Stockbridge (Georgia) | 605.11 mi (973.82 km) |
| Lyons to Stockton (California) | 1,783.59 mi (2,870.41 km) |
| Lyons to Stone Ridge (Virginia) | 575.35 mi (925.94 km) |
| Lyons to Stonecrest (Georgia) | 596.35 mi (959.72 km) |
| Lyons to Stony Brook (New York) | 763.52 mi (1,228.77 km) |
