| Lyons to Scottsboro (Alabama) | 504.46 mi (811.86 km) |
| Lyons to Scottsdale (Arizona) | 1,422.38 mi (2,289.11 km) |
| Lyons to Scranton (Pennsylvania) | 628.01 mi (1,010.68 km) |
| Lyons to Seabrook (Maryland) | 608.92 mi (979.96 km) |
| Lyons to Seabrook (Texas) | 936.27 mi (1,506.79 km) |
| Lyons to Seaford (New York) | 747.66 mi (1,203.24 km) |
| Lyons to Seagoville (Texas) | 793.35 mi (1,276.78 km) |
| Lyons to Seal Beach (California) | 1,732.70 mi (2,788.50 km) |
| Lyons to Searcy (Arkansas) | 500.73 mi (805.84 km) |
| Lyons to Seaside (California) | 1,842.54 mi (2,965.27 km) |
| Lyons to SeaTac (Washington) | 1,724.40 mi (2,775.16 km) |
| Lyons to Seattle (Washington) | 1,725.69 mi (2,777.24 km) |
| Lyons to Sebastian (Florida) | 1,053.92 mi (1,696.13 km) |
| Lyons to Sebring (Florida) | 1,053.67 mi (1,695.72 km) |
| Lyons to Secaucus (New Jersey) | 716.70 mi (1,153.41 km) |
