| Lyons to Oswego (Illinois) | 28.14 mi (45.29 km) |
| Lyons to Oswego (New York) | 585.92 mi (942.95 km) |
| Lyons to Otsego (Minnesota) | 375.83 mi (604.84 km) |
| Lyons to Ottawa (Illinois) | 60.85 mi (97.93 km) |
| Lyons to Ottawa (Kansas) | 450.96 mi (725.75 km) |
| Lyons to Ottumwa (Iowa) | 244.50 mi (393.48 km) |
| Lyons to Overland (Missouri) | 253.76 mi (408.38 km) |
| Lyons to Overland Park (Kansas) | 414.09 mi (666.41 km) |
| Lyons to Overlea (Maryland) | 616.11 mi (991.53 km) |
| Lyons to Oviedo (Florida) | 982.08 mi (1,580.51 km) |
| Lyons to Owasso (Oklahoma) | 574.41 mi (924.43 km) |
| Lyons to Owatonna (Minnesota) | 315.67 mi (508.03 km) |
| Lyons to Owensboro (Kentucky) | 282.60 mi (454.80 km) |
| Lyons to Owings Mills (Maryland) | 601.24 mi (967.60 km) |
| Lyons to Owosso (Michigan) | 203.04 mi (326.76 km) |
