| Lyons to Odessa (Texas) | 1,053.74 mi (1,695.83 km) |
| Lyons to Ogden (Utah) | 1,245.81 mi (2,004.95 km) |
| Lyons to Oildale (California) | 1,731.17 mi (2,786.05 km) |
| Lyons to Ojus (Florida) | 1,179.04 mi (1,897.47 km) |
| Lyons to Okemos (Michigan) | 184.76 mi (297.34 km) |
| Lyons to Oklahoma City (Oklahoma) | 681.77 mi (1,097.20 km) |
| Lyons to Okmulgee (Oklahoma) | 614.48 mi (988.91 km) |
| Lyons to Olathe (Kansas) | 420.34 mi (676.47 km) |
| Lyons to Old Jamestown (Missouri) | 242.97 mi (391.03 km) |
| Lyons to Oldsmar (Florida) | 994.03 mi (1,599.74 km) |
| Lyons to Olean (New York) | 482.51 mi (776.52 km) |
| Lyons to Olive Branch (Mississippi) | 485.88 mi (781.95 km) |
| Lyons to Olivehurst (California) | 1,772.53 mi (2,852.61 km) |
| Lyons to Olney (Maryland) | 593.62 mi (955.34 km) |
| Lyons to Olympia (Washington) | 1,752.62 mi (2,820.57 km) |
