| Lyons to Cloverleaf (Texas) | 926.43 mi (1,490.95 km) |
| Lyons to Cloverly (Maryland) | 598.23 mi (962.75 km) |
| Lyons to Clovis (California) | 1,727.27 mi (2,779.78 km) |
| Lyons to Clovis (New Mexico) | 976.45 mi (1,571.45 km) |
| Lyons to Clute (Texas) | 980.09 mi (1,577.30 km) |
| Lyons to Coachella (California) | 1,636.89 mi (2,634.32 km) |
| Lyons to Coalinga (California) | 1,778.08 mi (2,861.55 km) |
| Lyons to Coamo (Puerto Rico) | 2,070.51 mi (3,332.17 km) |
| Lyons to Coatesville (Pennsylvania) | 638.68 mi (1,027.86 km) |
| Lyons to Cockeysville (Maryland) | 607.82 mi (978.19 km) |
| Lyons to Cocoa (Florida) | 1,008.99 mi (1,623.81 km) |
| Lyons to Cocoa Beach (Florida) | 1,015.27 mi (1,633.92 km) |
| Lyons to Coconut Creek (Florida) | 1,157.49 mi (1,862.80 km) |
| Lyons to Coeur d'Alene (Idaho) | 1,469.01 mi (2,364.15 km) |
| Lyons to Cohoes (New York) | 723.43 mi (1,164.24 km) |
