| Luxembourg to Southern Pines (North Carolina) | 4,235.58 mi (6,816.50 km) |
| Luxembourg to Southfield (Michigan) | 4,056.26 mi (6,527.92 km) |
| Luxembourg to Southgate (Michigan) | 4,066.40 mi (6,544.23 km) |
| Luxembourg to Southlake (Texas) | 5,056.06 mi (8,136.93 km) |
| Luxembourg to Spanaway (Washington) | 5,082.49 mi (8,179.48 km) |
| Luxembourg to Spanish Fork (Utah) | 5,177.99 mi (8,333.16 km) |
| Luxembourg to Spanish Lake (Missouri) | 4,496.49 mi (7,236.40 km) |
| Luxembourg to Spanish Springs (Nevada) | 5,444.41 mi (8,761.93 km) |
| Luxembourg to Sparks (Nevada) | 5,450.59 mi (8,771.88 km) |
| Luxembourg to Spartanburg (South Carolina) | 4,351.60 mi (7,003.23 km) |
| Luxembourg to Spearfish (South Dakota) | 4,692.05 mi (7,551.12 km) |
| Luxembourg to Speedway (Indiana) | 4,295.69 mi (6,913.25 km) |
| Luxembourg to Spencer (Iowa) | 4,465.91 mi (7,187.19 km) |
| Luxembourg to Spokane (Washington) | 4,921.37 mi (7,920.19 km) |
| Luxembourg to Spokane Valley (Washington) | 4,916.36 mi (7,912.11 km) |
