| Lousa to Southern Pines (North Carolina) | 3,802.04 mi (6,118.80 km) |
| Lousa to Southfield (Michigan) | 3,764.41 mi (6,058.24 km) |
| Lousa to Southgate (Michigan) | 3,769.78 mi (6,066.88 km) |
| Lousa to Southlake (Texas) | 4,748.81 mi (7,642.46 km) |
| Lousa to Spanaway (Washington) | 5,182.34 mi (8,340.18 km) |
| Lousa to Spanish Fork (Utah) | 5,096.57 mi (8,202.14 km) |
| Lousa to Spanish Lake (Missouri) | 4,204.86 mi (6,767.06 km) |
| Lousa to Spanish Springs (Nevada) | 5,436.91 mi (8,749.87 km) |
| Lousa to Sparks (Nevada) | 5,442.67 mi (8,759.13 km) |
| Lousa to Spartanburg (South Carolina) | 3,935.60 mi (6,333.74 km) |
| Lousa to Spearfish (South Dakota) | 4,595.45 mi (7,395.67 km) |
| Lousa to Speedway (Indiana) | 3,985.88 mi (6,414.66 km) |
| Lousa to Spencer (Iowa) | 4,278.17 mi (6,885.05 km) |
| Lousa to Spokane (Washington) | 4,982.99 mi (8,019.34 km) |
| Lousa to Spokane Valley (Washington) | 4,976.18 mi (8,008.38 km) |
