| Louisville to Storm Lake (Iowa) | 589.37 mi (948.50 km) |
| Louisville to Storrs (Connecticut) | 751.56 mi (1,209.52 km) |
| Louisville to Stoughton (Wisconsin) | 378.40 mi (608.98 km) |
| Louisville to Stow (Ohio) | 305.68 mi (491.95 km) |
| Louisville to Streamwood (Illinois) | 297.96 mi (479.52 km) |
| Louisville to Streator (Illinois) | 265.33 mi (427.00 km) |
| Louisville to Streetsboro (Ohio) | 312.03 mi (502.16 km) |
| Louisville to Strongsville (Ohio) | 297.25 mi (478.37 km) |
| Louisville to Stuart (Florida) | 820.13 mi (1,319.87 km) |
| Louisville to Stuarts Draft (Virginia) | 359.67 mi (578.84 km) |
| Louisville to Sturgis (Michigan) | 251.30 mi (404.42 km) |
| Louisville to Suamico (Wisconsin) | 464.17 mi (747.01 km) |
| Louisville to Sudley (Virginia) | 442.90 mi (712.78 km) |
| Louisville to Suffern (New York) | 644.60 mi (1,037.38 km) |
| Louisville to Suffolk (Virginia) | 504.39 mi (811.74 km) |
