| Louisville to St. Simons (Georgia) | 540.06 mi (869.14 km) |
| Louisville to Stafford (Texas) | 818.48 mi (1,317.21 km) |
| Louisville to Stallings (North Carolina) | 347.94 mi (559.95 km) |
| Louisville to Stamford (Connecticut) | 673.90 mi (1,084.54 km) |
| Louisville to Stanford (California) | 1,981.49 mi (3,188.90 km) |
| Louisville to Stanton (California) | 1,823.92 mi (2,935.31 km) |
| Louisville to Star (Idaho) | 1,644.50 mi (2,646.56 km) |
| Louisville to Starkville (Mississippi) | 370.71 mi (596.59 km) |
| Louisville to State College (Pennsylvania) | 453.17 mi (729.30 km) |
| Louisville to Staten Island (New York) | 635.92 mi (1,023.42 km) |
| Louisville to Statesboro (Georgia) | 451.97 mi (727.37 km) |
| Louisville to Statesville (North Carolina) | 310.78 mi (500.15 km) |
| Louisville to Staunton (Virginia) | 357.79 mi (575.80 km) |
| Louisville to Steamboat Springs (Colorado) | 1,140.26 mi (1,835.06 km) |
| Louisville to Steiner Ranch (Texas) | 881.58 mi (1,418.77 km) |
