| Louisville to Silver Firs (Washington) | 1,940.53 mi (3,122.98 km) |
| Louisville to Silver Spring (Maryland) | 469.37 mi (755.38 km) |
| Louisville to Silver Springs Shores (Florida) | 659.38 mi (1,061.17 km) |
| Louisville to Silverdale (Washington) | 1,963.68 mi (3,160.24 km) |
| Louisville to Silverton (Oregon) | 1,957.87 mi (3,150.88 km) |
| Louisville to Simi Valley (California) | 1,854.75 mi (2,984.94 km) |
| Louisville to Simpsonville (South Carolina) | 303.17 mi (487.91 km) |
| Louisville to Sioux City (Iowa) | 639.30 mi (1,028.86 km) |
| Louisville to Sioux Falls (South Dakota) | 687.06 mi (1,105.72 km) |
| Louisville to Skokie (Illinois) | 289.29 mi (465.57 km) |
| Louisville to Sleepy Hollow (New York) | 657.87 mi (1,058.74 km) |
| Louisville to Slidell (Louisiana) | 593.14 mi (954.57 km) |
| Louisville to Smithfield (North Carolina) | 443.11 mi (713.11 km) |
| Louisville to Smithfield (Utah) | 1,402.87 mi (2,257.69 km) |
| Louisville to Smithville (Missouri) | 487.98 mi (785.32 km) |
