| Louisville to Shelton (Connecticut) | 698.44 mi (1,124.04 km) |
| Louisville to Shelton (Washington) | 1,980.87 mi (3,187.90 km) |
| Louisville to Shenandoah (Louisiana) | 617.12 mi (993.16 km) |
| Louisville to Shepherdsville (Kentucky) | 13.09 mi (21.07 km) |
| Louisville to Sheridan (Wyoming) | 1,190.17 mi (1,915.39 km) |
| Louisville to Sherman (Texas) | 688.98 mi (1,108.80 km) |
| Louisville to Sherrelwood (Colorado) | 1,043.47 mi (1,679.30 km) |
| Louisville to Sherwood (Arkansas) | 429.91 mi (691.88 km) |
| Louisville to Sherwood (Oregon) | 1,961.34 mi (3,156.47 km) |
| Louisville to Shiloh (Illinois) | 232.73 mi (374.54 km) |
| Louisville to Shiloh (Ohio) | 137.03 mi (220.53 km) |
| Louisville to Shiloh (Pennsylvania) | 490.98 mi (790.15 km) |
| Louisville to Shirley (New York) | 704.26 mi (1,133.39 km) |
| Louisville to Shively (Kentucky) | 9.21 mi (14.83 km) |
| Louisville to Shoreline (Washington) | 1,948.60 mi (3,135.97 km) |
