| Louisville to Savannah (Georgia) | 493.38 mi (794.02 km) |
| Louisville to Sayreville (New Jersey) | 625.36 mi (1,006.43 km) |
| Louisville to Sayville (New York) | 692.91 mi (1,115.14 km) |
| Louisville to Scaggsville (Maryland) | 477.47 mi (768.42 km) |
| Louisville to Scarsdale (New York) | 660.99 mi (1,063.76 km) |
| Louisville to Schaumburg (Illinois) | 296.38 mi (476.98 km) |
| Louisville to Schenectady (New York) | 693.39 mi (1,115.90 km) |
| Louisville to Schererville (Indiana) | 248.36 mi (399.70 km) |
| Louisville to Schertz (Texas) | 934.44 mi (1,503.84 km) |
| Louisville to Schiller Park (Illinois) | 287.11 mi (462.05 km) |
| Louisville to Schofield Barracks (Hawaii) | 4,381.88 mi (7,051.96 km) |
| Louisville to Scotchtown (New York) | 640.27 mi (1,030.42 km) |
| Louisville to Scottdale (Georgia) | 311.79 mi (501.77 km) |
| Louisville to Scotts Valley (California) | 1,978.97 mi (3,184.84 km) |
| Louisville to Scottsbluff (Nebraska) | 984.81 mi (1,584.91 km) |
