| Louisville to Olympia Heights (Florida) | 913.85 mi (1,470.69 km) |
| Louisville to Omaha (Nebraska) | 592.45 mi (953.45 km) |
| Louisville to On Top of the World Designated Place (Florida) | 655.07 mi (1,054.23 km) |
| Louisville to Onalaska (Wisconsin) | 489.90 mi (788.42 km) |
| Louisville to Oneida (New York) | 623.35 mi (1,003.18 km) |
| Louisville to Oneonta (New York) | 630.73 mi (1,015.06 km) |
| Louisville to Ontario (California) | 1,797.61 mi (2,892.97 km) |
| Louisville to Ontario (Oregon) | 1,669.76 mi (2,687.22 km) |
| Louisville to Opa-locka (Florida) | 904.03 mi (1,454.90 km) |
| Louisville to Opelika (Alabama) | 380.67 mi (612.63 km) |
| Louisville to Opelousas (Louisiana) | 642.56 mi (1,034.10 km) |
| Louisville to Orange (California) | 1,814.51 mi (2,920.18 km) |
| Louisville to Orange (Texas) | 723.26 mi (1,163.98 km) |
| Louisville to Orange City (Florida) | 685.24 mi (1,102.78 km) |
| Louisville to Orangeburg (South Carolina) | 419.40 mi (674.95 km) |
