| Louisville to Des Plaines (Illinois) | 292.55 mi (470.81 km) |
| Louisville to Desert Hot Springs (California) | 1,741.69 mi (2,802.97 km) |
| Louisville to DeSoto (Texas) | 738.81 mi (1,189.01 km) |
| Louisville to Destin (Florida) | 538.98 mi (867.41 km) |
| Louisville to Destrehan (Louisiana) | 627.64 mi (1,010.09 km) |
| Louisville to Detroit (Michigan) | 320.76 mi (516.21 km) |
| Louisville to Diamond Bar (California) | 1,809.88 mi (2,912.71 km) |
| Louisville to Diamond Springs (California) | 1,893.24 mi (3,046.88 km) |
| Louisville to Dickinson (North Dakota) | 1,057.19 mi (1,701.38 km) |
| Louisville to Dickinson (Texas) | 807.85 mi (1,300.11 km) |
| Louisville to Dickson (Tennessee) | 173.38 mi (279.03 km) |
| Louisville to Difficult Run (Virginia) | 451.38 mi (726.42 km) |
| Louisville to Dinuba (California) | 1,846.76 mi (2,972.07 km) |
| Louisville to Discovery Bay (California) | 1,944.02 mi (3,128.59 km) |
| Louisville to Dix Hills (New York) | 680.64 mi (1,095.39 km) |
